David will be sad to see Jamie exit
Jamie bows out at Christmas after appearing in the role of Derek Branning for around a year.
David, who plays Joey Branning, told Inside Soap: "I'm sad, all my early memories of being in EastEnders are with Jamie. Jamie's been so generous with his time and really looked after me.
"But I doubt he'll be sad for long because I know he'll move on to other great jobs."
Asked how his character will react to his dad's exit, he said: "You'd think he'd shrug it off. But Joey is all over the place, so his reaction may be surprising."
Viewers have seen Joey fall for his cousin Lauren, played by Jacqueline Jossa, in the BBC One soap.
David said: "If they had grown up together or played together as kids, then I could understand people thinking it's creepy or weird. But they've met as adults and it's only because they've been told they are cousins that they even know they're related.
"With the Brannings being the Brannings, it's bound to kick off. They won't be very happy about this at all."